Which is safer rosuvastatin or atorvastatin?

Which is safer rosuvastatin or atorvastatin?

Atorvastatin was the safest statin as it resulted in the least number of patients at the end of 2 years of treatment with the new onset of microalbuminuria (10.9%) followed by rosuvastatin (14.3%) and then pravastatin (26.6%).

Is rosuvastatin more effective than atorvastatin?

Rosuvastatin was more efficacious than the same dose of atorvastatin (1:1 dose ratio) or a 2 times higher dose (1:2 dose ratio) of atorvastatin. There was no significant difference between rosuvastatin and a 4 times higher dose of atorvastatin (1:4 dose ratio).

Which statin has the lowest risk of drug interactions?

As fluvastatin, pravastatin, rosuvastatin are primarily metabolized by CYP2C9, they are less subject to drug interaction than other statins.

What statin is the safest?

Simvastatin and pravastatin had the best safety profile, according to this review. Overall, the researchers found a 9 percent increased risk of type 2 diabetes in people taking statins.

Which is better tolerated Crestor or Lipitor?

Is Crestor safer than Lipitor? Crestor and Lipitor are both well tolerated. Any drug has side effects, with some rare but serious potential side effects, too. Studies (see above section) have shown that both medicines were tolerated well in trials.

Is Crestor better tolerated than Lipitor?

Despite this, there was no significant difference between the two drugs in how well they decreased the volume of atherosclerotic buildup in the arteries. Both Crestor and Lipitor are generally well tolerated with a similar rate of side effects.

Can I switch from atorvastatin to rosuvastatin?

Conclusion: Switching from 10mg atorvastatin to 5mg rosuvastatin may be a useful therapeutic option to reduce sd LDL-C levels in Japanese hypercholesterolemic patients with T2DM.

Is Crestor better than Lipitor?

Both Lipitor and Crestor are excellent medications to help improve high cholesterol and to decrease your risk of heart attacks and strokes. In studies, Crestor was more effective at lowering total cholesterol levels and raising HDL levels (Jones, 2003).

Is rosuvastatin the best statin?

Conclusion: Rosuvastatin was more effective than other statins in reducing LDL, triglyceride (except vs atorvastatin), and total cholesterol levels. Significantly more patients taking rosuvastatin than patients taking other statins attained their LDL goals.

What are the dangers of atorvastatin?

Common Lipitor side effects are diarrhea, upset stomach, muscle and joint pain, and changes in some blood tests, according to Pfizer Inc. The drug label also warns of serious side effects such as liver problems and muscle problems that can lead to kidney failure.

Can I switch from rosuvastatin to atorvastatin?

Abstract. Background: Now that generic atorvastatin has become available, a process of switching from rosuvastatin to atorvastatin may occur and could persist until the patent on branded rosuvastatin expires. It is important to understand the impact that such therapy may have on patients’ cardiovascular (CV) health.

Does rosuvastatin cause liver damage?

Rosuvastatin is a commonly used cholesterol lowering agent (statin) that is associated with mild, asymptomatic and self-limited serum aminotransferase elevations during therapy, and rarely with clinically apparent acute liver injury.

Is Crestor better than atorvastatin?

Lipitor: which is better for me? Crestor (rosuvastatin) is more potent and causes a more significant lowering of total cholesterol, but Crestor and Lipitor (atorvastatin) similarly decrease the buildup of plaques in the blood vessels.

Should you take Crestor or Lipitor?

The study concluded that Crestor lowered LDL cholesterol by 8.2% more than Lipitor, and Crestor lowered total cholesterol significantly more than all the other statins studied. Crestor also increased HDL cholesterol (the good kind of cholesterol) more than Lipitor did.

Is rosuvastatin being recalled?

In September 2021, recalls and notifications for medicines were issued on: Class 4 Medicines Defect Information, Rosuvastatin 5 mg, 10 mg, 20 mg and 40 mg film-coated tablets (EL (21)A/21). Issued 9 September 2021.

Can rosuvastatin be taken in place of atorvastatin?

Two other statins, atorvastatin (Lipitor) and rosuvastatin (Crestor) aren’t broken down as readily, so you can take them any time. To continue reading this article, you must log in . Subscribe to Harvard Health Online for immediate access to health news and information from Harvard Medical School.

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Is atorvastatin cheaper than simvastatin?

The costs of generic simvastatin and atorvastatin are both fairly low, with generic simvastatin being slightly less expensive. Atorvastatin is usually $25–40 per month. The brand-name drugs are much more expensive than their generics. Zocor, the brand for simvastatin, is about $200–250 per month.